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Innovations for communities

Health Research and Development

Health innovations built for those most affected, and within their reach

Overview

WACI Health advocates for African-led health research and development (R&D) that responds to African priorities, reflects community needs and is backed by sustainable domestic financing. Its work covers how research is financed and governed, how communities take part in it, and whether the innovations it produces reach the people who need them, from long-acting HIV prevention to shorter TB treatments and lifesaving medicines for childbirth.

Africa carries roughly a quarter of the world’s disease burden, yet African countries spend on average 0.45% of their GDP on research and development, against a global average of 1.7% and well short of the African Union’s target of 1%. Africa CDC estimates that meeting that target, with 15% of it going to health research, could add US$668 billion to African economies over 20 years.

This work includes its support for the Coalition for Health Research and Development (CHReaD), hosted by Amref Health Africa in Kenya. When African governments invest in their own research systems and listen to communities, researchers can set agendas that match local needs, and new products can be designed from the start to be affordable and suited to the people who will use them.

Health Research and Development

Purpose

  1. 01 Increase sustained domestic investment in health R&D, in line with national and African Union commitments.
  2. 02 Put communities and human rights at the centre of clinical research, from trial design and ethics to the introduction of new products.
  3. 03 Speed up equitable, affordable access to new health innovations, including long-acting HIV prevention, shorter TB treatments and lifesaving maternal health medicines.
  4. 04 Build the capacity of civil society and policymakers to use evidence, and hold governments and partners to account for their commitments on R&D policy and financing.
Health research advocates and officials gathered for a meeting
Health Research and Development

What We Do

WACI Health works through national and regional coalitions to build support for health R&D, so that what works in one country can be tried in others. It is a founding member of CHReaD, where it sits on the domestic resource mobilisation working group and co-chairs the communications working group. Founded in 2015, CHReaD connects civil society organisations, research institutions, universities, government departments and private companies in Kenya and across East Africa. Its members push for the policies, regulation and financing that let health research and innovation flourish, and make the case for greater investment in health research, development and innovation as part of universal health coverage.

So that clinical research is ethical, inclusive and designed around the needs of those most affected, WACI Health sits on the community advisory board of REACH (Research to Expand Access to Heat-stable Carbetocin for the Treatment of Postpartum Haemorrhage), a trial on treating heavy bleeding after childbirth, a leading cause of maternal death. It is also on the steering committee of PEARLS (Preventing pre-eclampsia: Evaluating AspiRin Low-dose regimens following risk Screening), which is testing how best to use low-dose aspirin to prevent pre-eclampsia in women identified as at risk. Through AfNHi, WACI Health promotes ethical community engagement in HIV prevention trials.

Research reaches impact once solutions are approved, affordable and within reach. WACI Health supports shared regulatory standards and joint reviews across the continent, and pushes for fair prices and faster introduction of new tools, from long-acting HIV prevention to shorter TB treatments and medicines for safer childbirth.

A speaker at the Biomedical HIV Prevention Forum
Publications

Reports, briefs and statements

All resources
Cover of Research and Development for Health in Kenya: The Coalition for Health Research and Development (CHReaD) CHReaD

Research and Development for Health in Kenya: The Coalition for Health Research and Development (CHReaD)

2018

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Cover of Research and Policy Report on Investments in HIV R&D in Africa Health Research and Development

Research and Policy Report on Investments in HIV R&D in Africa

2023

A Publications publication from the WACI Health knowledge library, published in February 2023.

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Cover of Invest in HIV and Health R&D Statements

Invest in HIV and Health R&D

2022

A Statements publication from the WACI Health knowledge library, published in December 2022.

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Cover of The Bamako Call to Action on Research for Health Statements

The Bamako Call to Action on Research for Health

2022

A Statements publication from the WACI Health knowledge library, published in December 2022.

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Cover of Domestic Financing of The Kenya HIV AIDS Research Agenda 2014 – 2019 Policy Briefs

Domestic Financing of The Kenya HIV AIDS Research Agenda 2014 – 2019

2022

A Policy Briefs publication from the WACI Health knowledge library, published in December 2022.

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WACI Resource Library Publication
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